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Synthesis 2010(8): 1334-1338
DOI: 10.1055/s-0029-1218672
DOI: 10.1055/s-0029-1218672
PAPER
© Georg Thieme Verlag
Stuttgart ˙ New YorkStraightforward Access to α-Methylamines through Cross-Metathesis
Further Information
Received
15 December 2009
Publication Date:
05 February 2010 (online)
Publication History
Publication Date:
05 February 2010 (online)
Abstract
A two-step procedure involving cross-metathesis and reductive amination enables easy access to α-methylamines and α,α′-dimethyldiamines from a wide variety of terminal olefins.
Key words
amines - alkenes - metathesis - ruthenium - hydrogenation
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