Novel Synthetic Approaches to (Trifluoromethyl)triazoles
29 January 2010 (eFirst)
New synthetic procedures for the trifluoromethyl-substituted triazoles, 3-(trifluoromethyl)-4H-1,2,4-triazole and 4-(trifluoromethyl)-1H-1,2,3-triazole, have been elaborated. The target compounds were prepared from commercially available trifluoroacethydrazide (one step) and methyl propiolate (three steps), respectively.
fluorine - triazoles - trifluoromethyl group