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Synthesis 2010(5): 807-810
DOI: 10.1055/s-0029-1218603
DOI: 10.1055/s-0029-1218603
PAPER
© Georg Thieme Verlag
Stuttgart ˙ New YorkStereospecific Total Synthesis of (+)-Davana Acid, (+)-Nordavanone and (+)-Davanone
Weitere Informationen
Received
4 November 2009
Publikationsdatum:
11. Dezember 2009 (online)
Publikationsverlauf
Publikationsdatum:
11. Dezember 2009 (online)

Abstract
A short, total synthesis of (+)-davana acid, (+)-nordavanone and (+)-davanone, which are principle components of davana oil, is described. The notable features are the use of the Evans syn aldol reaction and cyclic ether formation by an intramolecular SN2 displacement reaction as key steps.
Key words
Evans aldol - cyclic ether - (-)-linalool - natural product - davana oil
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