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Synlett 2009(20): 3328-3332  
DOI: 10.1055/s-0029-1218358
LETTER
© Georg Thieme Verlag Stuttgart ˙ New York

Straightforward Synthesis of 2-Acetamido-2-deoxy-β-d-glucopyranosyl Esters under Microwave Conditions

Rose Haddoub, Nicolas Laurent, Marco M. Meloni, Sabine L. Flitsch*
Manchester Interdisciplinary Biocentre and School of Chemistry, The University of Manchester, 131 Princess Street, Manchester M1 7DN, UK
Fax: +44(161)2751311; e-Mail: sabine.flitsch@manchester.ac.uk;
Further Information

Publication History

Received 10 September 2009
Publication Date:
11 November 2009 (online)

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Abstract

A straightforward synthesis of 2-acetamido-2-deoxy-β-d-glucopyranosyl esters from unprotected GlcNAc oxazoline has been achieved under catalyst-free, microwave conditions.

Key words

glycosyl esters - glycomimetics - GlcNAc oxazoline - microwaves - catalyst-free

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