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Synthesis 2009(22): 3785-3790  
DOI: 10.1055/s-0029-1218149
PAPER
© Georg Thieme Verlag Stuttgart ˙ New York

Open-Vessel Microwave-Mediated [2+2+2]-Cyclotrimerization Reactions

Douglas D. Young, Jesse A. Teske, Alexander Deiters*
Department of Chemistry, North Carolina State University, Raleigh, NC 27607, USA
Fax: +1(919)5155079; e-Mail: alex_deiters@ncsu.edu;
Further Information

Publication History

Received 27 June 2009
Publication Date:
07 October 2009 (online)

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Abstract

[2+2+2]-Cyclotrimerization reactions often suffer from low reaction rates and low chemoselectivity. We are reporting a solution to both problems through the use of open-vessel conditions for microwave-mediated cyclotrimerization reactions.

Key words

[2+2+2] cyclotrimerization - alkynes - microwave - bicyclic compounds - transition metal catalysis

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