A New and Simple Synthesis of Sulfonyl Ureas from Sulfonamides and N-Alkyl-1,2,4-dithiazolidine-3,5-diones

Abstract

A new, short, and simple synthetic approach to sulfonyl ureas is reported. The method involves the transformation of readily synthesized N-alkyl-1,2,4-dithiazolidine-3,5-diones by reaction with primary sulfonamides. Sulfonyl ureas were obtained in moderate to high yields.

Key words

sulfonyl ureas - isocyanates - sulfonamides - heterocycles - protecting group

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