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Synthesis 2009(14): 2316-2318  
DOI: 10.1055/s-0029-1216815
SHORTPAPER
© Georg Thieme Verlag Stuttgart ˙ New York

Synthesis of Symmetrical Ketones from Grignard Reagents and 1,1′-Carbonyldiimidazole

Daniela Bottalico, Vito Fiandanese, Giuseppe Marchese*, Angela Punzi
Dipartimento di Chimica, Università di Bari, Via Orabona 4, 70126 Bari, Italy
Fax: +39(80)5442075; e-Mail: marchese@chimica.uniba.it;
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Publikationsverlauf

Received 19 February 2009
Publikationsdatum:
14. Mai 2009 (online)

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Abstract

Coupling reactions of 1,1′-carbonyldiimidazole with Grignard reagents provide a rapid and straightforward method for the synthesis of symmetrical ketones.

Key words

Grignard reactions - coupling - acylations - 1,1′-carbonyldiimidazole - ketones

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