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Synthesis 2009(11): 1858-1864  
DOI: 10.1055/s-0029-1216798
PAPER
© Georg Thieme Verlag Stuttgart ˙ New York

Recyclization Reactions of 5-Formyl-1,3-dimethyluracil with Electron-Rich Amino Heterocycles

Andrey P. Mityuka, Dmitriy M. Volochnyuk*a,b, Sergey V. Ryabukhina,c, Andrey S. Plaskona,c, Alexander Shivanyuk*a,c, Andrey A. Tolmachevc
a ‘Enamine Ltd.’, 23 A. Matrosova St, 01103 Kyiv, Ukraine
Fax: +380(44)5373253; e-Mail: D.Volochnyuk@enamine.net; e-Mail: A.Shivanyuk@enamine.net;
b Institute of Organic Chemistry, National Academy of Sciences of Ukraine, Murmanska 5, 02094 Kyiv-94, Ukraine
c National Taras Shevchenko University, 62 Volodymyrska St, 01033 Kyiv-33, Ukraine
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Publikationsverlauf

Received 30 October 2008
Publikationsdatum:
12. Mai 2009 (online)

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Abstract

Recyclization reactions of 5-formyl-1,3-dimethyluracil with various electron-rich five- or six-membered amino heterocycles led to the formation of a series of fused heterocycles containing a nicotinic acid unit.

Key words

5-formyl-1,3-dimethyluracil - amino heterocycles - fused pyridines - fused-ring systems - recyclization reactions

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