Subscribe to RSS
Please copy the URL and add it into your RSS Feed Reader.
https://www.thieme-connect.de/rss/thieme/en/10.1055-s-00000131.xml
Download PDF
Synfacts 2008(12): 1322-1322
DOI: 10.1055/s-0028-1083591
DOI: 10.1055/s-0028-1083591
Metal-Mediated Synthesis
© Georg Thieme Verlag
Stuttgart ˙ New YorkRu-Catalyzed Selective Redox Isomerization of Propargylic Alcohols
B. M. Trost*, R. C. Livingston
Stanford University, USA
Further Information
Publication History
Publication Date:
20 November 2008 (online)
Significance
The authors report a novel method for performing the isomerization of propargylic alcohols in high yields to selectively provide (E)-enals and enones using a readily available catalyst. A propargylic hydride migration-based mechanism has been suggested in deuterium-labeling experiments.