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Synthesis 2009(6): 888-890  
DOI: 10.1055/s-0028-1083372
SHORTPAPER
© Georg Thieme Verlag Stuttgart ˙ New York

Synthesis of Glycoaminoxy Acids as Novel Sugar Building Blocks

Adeline Malapelle, Romain Ramozzi, Juan Xie*
PPSM, ENS Cachan, Institut d’Alembert, CNRS, Universud, 61 av. Président Wilson, 94230 Cachan, France
Fax: +33(1)47402454; e-Mail: joanne.xie@ens-cachan.fr;
Further Information

Publication History

Received 13 November 2008
Publication Date:
11 February 2009 (online)

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Abstract

Glycoaminoxy acids, a new class of sugar building blocks bearing both aminoxy and carboxylic acid functional groups on the sugar ring, have been efficiently synthesized from α-C-allyl glycosides. These compounds can be easily used for the synthesis of an N-oxy-amide-linked disaccharide and glycosyl amino acid mimetics.

Key words

glycoaminoxy acids - glycopeptides - glycomimetics - glycosides - oligosaccharides

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