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Synthesis 2009(6): 1036-1040  
DOI: 10.1055/s-0028-1083358
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© Georg Thieme Verlag Stuttgart ˙ New York

An Improved Process for the Synthesis of 4H-Imidazo[1,5-a][1,4]benzo­diazepines

Jie Yang, Yun Teng, Shamim Ara, Sundari Rallapalli, James M. Cook*
Department of Chemistry, University of Wisconsin-Milwaukee, Milwaukee, WI 53211, USA
Fax: +1(414)2295530; e-Mail: [email protected];
Further Information

Publication History

Received 5 September 2008
Publication Date:
11 February 2009 (online)

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Abstract

The construction of CNS active imidazo[1,5-a][1,4]benzodiazepines has been improved in a one-pot annulation process.

Key words

GABAA/Bz receptors - imidazo[1,5-a][1,4]benzodiazepines - ethyl isocyanoacetate - annulation

    References

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