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Synlett
DOI: 10.1055/a-2706-0614
Letter

Photoinduced and N-Bromosuccinimide Initiated Esterification of Aromatic acids and Terminal Alkynes with Alcohols

Authors

  • Han Liu

    1   Pharmaceutical School, Changde Vocational Technical College, Changde, China

  • Zhiyong Yang

    1   Pharmaceutical School, Changde Vocational Technical College, Changde, China
    2   Pharmaceutical School, Changde College, Changde, China

  • Jiaqi Yan

    1   Pharmaceutical School, Changde Vocational Technical College, Changde, China
    2   Pharmaceutical School, Changde College, Changde, China

  • Jing Guo

    1   Pharmaceutical School, Changde Vocational Technical College, Changde, China
    2   Pharmaceutical School, Changde College, Changde, China

Supported by: Scientific Research Foundation for Advanced Talents from Changde College
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A mild and convenient protocol for the esterification of aromatic acids and terminal alkynes with alcohols by visible-light catalysis strategy using N-bromosuccinimide (NBS) as additive has been developed. This protocol provides access to substituted aromatic esters and ɑ-ketoesters in moderateto good yields at room temperature. The advantage of this method is operational simplicity compared with other known methods.



Publication History

Received: 19 May 2025

Accepted after revision: 01 September 2025

Accepted Manuscript online:
19 September 2025

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