Electrochemically Driven Strategies Enabling the Construction of Carbon-Carbon/Carbon-Heteroatom Bonds

The scientific community has recently shown a significant interest in electro-organic synthesis, which has been recognized as a promising, environmentally friendly, and sustainable tool for organic synthesis. Here, the electric current acts as a reagent to drive chemical transformations, which avoids the usage of hazardous, oxidizing, and reducing reagents. Therefore, herein, we present an account of recent developments in electrochemical synthetic methodologies that were developed in our laboratory, such as the synthesis of tertiary alcohols, 3-selenylindoles, sulfenyl-phenanthrenes, spiro-cyclohexadienone indenes, β-hydroxy-selenides, 4-sulfenyl-isochromenones, and para-hydroxysulfonamides/acetanilides. We hope this account will provide the feasibility and further advancements in reaction design, mechanistic understanding, and the pertinence of electro-catalysis in academic and industry frameworks. 1 Introduction 2 Synthetic strategies 2.1 Synthesis of tertiary alcohols 2.2 Synthesis of 3-selenylindoles 2.3 Synthesis of fused sulfenyl-phenanthrenes and spiro-cyclohexadienone indenes 2.4 Synthesis of β-hydroxy-selenides 2.5 Synthesis of 4-sulfenyl-isochromenones 2.6 Synthesis of para-hydroxysulfonamides/acetanilides 3 Conclusion and outlook

Publication History

Received: 27 June 2025

Accepted after revision: 03 August 2025

Accepted Manuscript online:
04 August 2025