Reductive Synthesis of Azoxypyridines from Nitropyridines Using Hydroxides in Alcoholic Media

Abstract

The partial reduction of nitroarenes with hydroxides in alcoholic media is a venerable yet very direct approach to the synthesis of symmetrical azoxyarenes. Herein, the first application of this method to nitropyridines is disclosed, presenting its adaptation with these challenging but important substrates.

Key words

alcohols - azoxy - nitro - pyridine - reduction - synthetic methods

Publikationsverlauf

Eingereicht: 15. Oktober 2024

Angenommen nach Revision: 28. November 2024

Accepted Manuscript online:
28. November 2024

Artikel online veröffentlicht:
13. Januar 2025

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