Adjuvante und neoadjuvante Therapie des Melanoms

Dirk Debus; Axel Hauschild; Erwin S. Schultz

doi:10.1055/a-2453-8887

DMW - Deutsche Medizinische Wochenschrift, Table of Contents

Dtsch Med Wochenschr 2025; 150(10): 555-561
DOI: 10.1055/a-2453-8887

Dossier

Adjuvante und neoadjuvante Therapie des Melanoms

Adjuvant and neoadjuvant therapy of melanoma

Dirk Debus

,

Axel Hauschild

,

Erwin S. Schultz

Abstract

Die Behandlung des malignen Melanoms mit (neo-)adjuvanter Therapie stellt einen vielversprechenden Ansatz zur Verminderung von Rezidiven und Metastasierung dar. Gleichzeitig ist aufgrund des Risikos potenzieller Nebenwirkungen vorab eine Nutzen-Risiko-Abwägung unter Berücksichtigung des stadienabhängigen Rezidivrisikos erforderlich. Der Artikel zeigt die aktuelle Studienlage zur adjuvanten und neoadjuvanten Therapie auf.

Abstract

The treatment of malignant melanoma with (neo-)adjuvant therapy represents a promising approach to reducing recurrence and metastasis. At the same time, due to the risk of potential side effects, a risk-benefit assessment is required in advance, taking into account the stage-dependent risk of recurrence. The article presents the current study situation on adjuvant and neoadjuvant therapy.

Schlüsselwörter

Melanom - adjuvant - neoadjuvant - Nutzen-Risiko-Abwägung - pathologische Remission

Keywords

melanoma - adjuvant - neoadjuvant - risk-benefit assessment - pathological remission

Full Text

References

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