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Synlett 2025; 36(03): 242-245
DOI: 10.1055/a-2322-0816
DOI: 10.1055/a-2322-0816
letter
Electrochemical Nitro Reduction to Amines Using Pinacolborane as Reducing Agent
We are grateful for the financial support from the scientific research start-up funds of Jiangsu Food & Pharmaceutical Science College, No.4 Meicheng Road, Huai’an Higher Education Park, Jiangsu Province.
Abstract
Nitroaromatic compounds, as hazardous industrial pollutants, have long been extensively studied for their conversion into high-value aromatic amines. However, most of these transformation reactions require either transition-metal catalysts or high-temperature conditions. Therefore, we report an electrochemical approach utilizing pinacolborane as the reducing agent for the efficient reduction of nitroaromatic compounds. The reaction is characterized by its mild conditions and simplicity of operation, and it demonstrates excellent substrate adaptability and functional group compatibility.
Key words
electrochemistry - nitroaromatic compounds - nitro reduction to amine - organic synthesis - pinacolboraneSupporting Information
- Supporting information for this article is available online at https://doi.org/10.1055/a-2322-0816.
- Supporting Information
Publication History
Received: 03 April 2024
Accepted after revision: 07 May 2024
Accepted Manuscript online:
08 May 2024
Article published online:
27 May 2024
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