A novel and efficient visible-light-induced method is developed for the one-pot synthesis
of functionalized 2-aminothiazoles from easily accessible active methylene ketone
derivatives and different thioureas at room temperature. The mild reaction conditions,
green chemistry, straightforward work-up, and high yields of the products make this
procedure useful for the construction of 2-aminothiazole derivatives.
Key words
photocatalysis - 2-aminothiazoles - cyclization - free-radical reaction - heterocyclic
compounds