Acid-Mediated Synthesis of Chromeno[2,3-b]pyridine Derivatives via Condensation of 2-Amino-3-formylchromones and 1-(Methylthio)-2-nitroenamine Derivatives

Abstract

A convenient and effective protocol has been proposed for the synthesis of chromeno[2,3-b]pyridine derivatives via the CF₃SO₃H-catalyzed annulation of substituted 2-amino-3-formylchromones and various 1-(methylthio)-2-nitroenamine derivatives. This method is time-efficient, convenient, high-yielding, and exhibits a good functional group compatibility.

Key words

2-amino-3-formylchromone derivatives - chromeno[2,3-b]pyridine derivatives - (E)-N-methyl-1-(methylthio)-2-nitroethenamine (NMSM)

Publikationsverlauf

Eingereicht: 21. Januar 2022

Angenommen nach Revision: 07. März 2022

Accepted Manuscript online:
07. März 2022

Artikel online veröffentlicht:
25. April 2022

• References and Notes

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