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Synlett 2022; 33(08): 754-758
DOI: 10.1055/a-1790-2992
DOI: 10.1055/a-1790-2992
letter
Acid-Mediated Synthesis of Chromeno[2,3-b]pyridine Derivatives via Condensation of 2-Amino-3-formylchromones and 1-(Methylthio)-2-nitroenamine Derivatives
Authors
This work was supported by the Innovation Program of Shanghai Municipal Education Commission (201701070002E00037), and the National Key Research and Development Program of China (2017YFD0200505).
Abstract
A convenient and effective protocol has been proposed for the synthesis of chromeno[2,3-b]pyridine derivatives via the CF3SO3H-catalyzed annulation of substituted 2-amino-3-formylchromones and various 1-(methylthio)-2-nitroenamine derivatives. This method is time-efficient, convenient, high-yielding, and exhibits a good functional group compatibility.
Key words
2-amino-3-formylchromone derivatives - chromeno[2,3-b]pyridine derivatives - (E)-N-methyl-1-(methylthio)-2-nitroethenamine (NMSM)Supporting Information
- Supporting information for this article is available online at https://doi.org/10.1055/a-1790-2992.
- Supporting Information (PDF)
Publikationsverlauf
Eingereicht: 21. Januar 2022
Angenommen nach Revision: 07. März 2022
Accepted Manuscript online:
07. März 2022
Artikel online veröffentlicht:
25. April 2022
© 2022. Thieme. All rights reserved
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