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Dtsch Med Wochenschr 2020; 145(22): 1599-1605
DOI: 10.1055/a-1038-0102
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Diabeteskomplikationen – Diabetes und Nervensystem

Diabetes complications – diabetes and the nervous system
Svenja Meyhöfer
,
Sebastian M. Schmid
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Diabetes mellitus ist eine chronische Stoffwechselerkrankung, deren multiple Langzeitkomplikationen auch das Nervensystem betreffen. Rund 30 % der Diabetespatienten leiden unter den starken Beeinträchtigungen des subjektiven Wohlbefindens einer Polyneuropathie. Auch das Risiko für die Entwicklung kognitiver Einschränkungen und Demenz ist bei älteren Diabetespatienten erhöht. Eine schlechte Glukosestoffwechsellage über viele Jahre scheint ein entscheidender Risikofaktor für die Entwicklung dieser Diabeteskomplikationen zu sein.

Abstract

Diabetes mellitus is a chronic metabolic disease associated with multiple long-term complications. Besides macro- and microvascular complications, patient’s well-being can be severely impaired by complications affecting the nervous system. About 50 % of patients with diabetes suffer from polyneuropathy. Moreover, the risk of developing cognitive impairment and dementia is also increased in older people with diabetes. Insufficient glycemic control, young age at diagnosis of diabetes are discussed as risk factors for developing diabetes complications. The early identification and prevention of factors predicting diabetes complications that affect the nervous system are still challenging and in need for further research.

Schlüsselwörter

Diabeteskomplikationen - Polyneuropathie - distal-symmetrische sensomotorische Polyneuropathie (DSPN) - Neurodegeneration - GLP-1-Rezeptoragonist

Key words

diabetes complications - polyneuropathy - distal Symmetrical Sensorimotor Polyneuropathy (DSPN) - neurodegeneration - GLP-1 receptor agonist.


Publication History

Article published online:
03 November 2020

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