Abstract
The palladium-catalyzed ureidation reaction of 2-chloropyridines can be regioselectively
performed in good yield, with both aryl and aliphatic ureas, using xantphos as the
ligand, Pd(OAc)2 as the source of palladium, NaOt -Bu/H2 O or NaOH/H2 O as the base, and dioxane as the solvent
Key words
palladium - catalysis - cross-coupling - pyridines - ureidation
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