Abstract
A highly diastereo- and enantioselective entry to higher order ketopolyols, employing
boron-mediated aldol reactions of a chiral dihydroxyacetone equivalent, is reported.
The differentially protected products should prove as useful building blocks for polyhydroxylated
natural product synthesis.
Key words
chiral dihydroxyacetone equivalent - α-substituted ketones - aldol reactions - polyols
- asymmetric synthesis
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