Download PDF
Synthesis 1994; 1994(8): 765-766
DOI: 10.1055/s-1994-25565
short paper
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.

Studies on Isocyanides and Related Compounds: A Novel Synthesis of Pyrroles via Ugi Reaction

Ricardo Bossio* , Stefano Marcaccini, Roberto Pepino
  • *CNR, Centro di Studio sulla Chimica e la Struttura dei Composti Eterociclici e loro Applicazioni, Dipartimento di Chimica Organica "Ugo Schiff", Università di Firenze, via Gino Capponi 9, I-50121 Firenze, Italy
Further Information

Publication History

Publication Date:
17 September 2002 (online)

 PDF Download  Permissions and Reprints All articles of this category

A series of N-substituted 1,3-diaryl-4-cyano-2,5-dihydro-5-oxopyrrole-2-carboxamides 9 is obtained by reacting arylglyoxal anils 6 with isocyanides 3 and cyanoacetic acid (2). Compounds 9 react quickly with diazomethane to give N-substituted 1, 3-diaryl-4-cyano-5-methoxypyrrole-2-carboxamides 12.