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Synthesis 1989; 1989(3): 179-181
DOI: 10.1055/s-1989-27186
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Acyl Silanes. Reagents for Diastereoselective Aldol Condensations

Dieter Schinzer*
  • *Department of Chemistry, University of California, Berkeley, CA 94720, USA
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Publication History

Publication Date:
17 September 2002 (online)

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The acyl silanes 4a-c have been prepared and the stereochemistry of their aldol reactions with aldehydes have been investigated; the ß-hydroxy ketones obtained were transformed into ß-hydroxy acids by simple oxidation with basic hydrogen peroxide.