Renale Sympathikusdenervation bei arterieller Hypertonie – Pro

Schlüsselwörter

therapieresistente Hypertonie - neue Behandlungsmethode - interventionelle Nieren- arteriendenervation - Symplicity - pleiotrope Effekte

Keywords

treatment-resistant hypertension - new treatment option - catheter-based renal denervation - Symplicity - pleiotropic effects

• Literatur

• 1 Brandt MC, Mahfoud F, Reda S et al. Renal sympathetic denervation reduces left ventricular hypertrophy and improves cardiac function in patients with resistant hypertension. J Am Coll Cardiol 2012; 59: 901-909
• 2 Esler MD, Krum H, Sobotka PA et al. Renal sympathetic denervation in patients with treatment-resistant hypertension (the symplicity htn-2 trial). Lancet 2010; 376: 1903-1909
• 3 Mahfoud F, Himmel F, Ukena C et al. Treatment strategies for resistant arterial hypertension. Dtsch Arztebl Int 2011; 108: 725-731
• 4 Mahfoud F, Schlaich M, Kindermann I et al. Effect of renal sympathetic denervation on glucose metabolism in patients with resistant hypertension. Circulation 2011; 123: 1940-1946
• 5 Mahfoud F, Vonend O, Bruck H et al. Interventionelle renale Sympathikusdenervation zur Behandlung der therapieresistenten Hypertonie. Dtsch Med Wochenschr 2011; 136: 2418-2424
• 6 Symplicity HTN-1 Investigators. Catheter-based renal sympathetic denervation for resistant hypertension: Durability of blood pressure reduction out to 24 months. Hypertension 2011; 57: 911-917
• 7 Witkowski A, Prejbisz A, Florczak E et al. Effects of renal sympathetic denervation on blood pressure, sleep apnea course, and glycemic control in patients with resistant hypertension and sleep apnea. Hypertension 2011; 58: 559-565