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Synthesis 2004(9): 1359-1362
DOI: 10.1055/s-2004-822397
DOI: 10.1055/s-2004-822397
PAPER
© Georg Thieme Verlag Stuttgart · New YorkFacile One-Pot Synthesis of Di- and Tri-Substituted Furans From Acyl Isocyanates Using Trimethylsilyldiazomethane
Further Information
Received
2 May 2004
Publication Date:
08 June 2004 (online)
Publication History
Publication Date:
08 June 2004 (online)
Abstract
The Diels-Alder reaction of 2-substituted 4-(trimethylsilyloxy)oxazoles, which were prepared in situ from trimethylsilyldiazomethane and acyl isocyanates, with dimethyl acetylenedicarboxylate or ethyl propiolate gave furan-3,4-dicarboxylic or furan-3-carboxylic esters in good yields.
Key words
acyl isocyanates - Diels-Alder reaction - furans - oxazoles - trimethylsilyldiazomethane
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