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DOI: 10.1055/s-0031-1289732
Convenient Chlorination of Some Special Aromatic Compounds Using N-Chlorosuccinimide
Publication History
Publication Date:
01 March 2012 (online)

Abstract
Some chlorinated aromatic compounds, including indole, benzofuran, carbazole, pyridine and aniline derivatives, are difficult to obtain through convenient chlorination. We herein report their efficient synthesis through chlorination with N-chlorosuccinimide (NCS). Optimization of the reaction conditions, including the temperature and the choice of solvent, was also investigated. This approach, which is characterized by a facile procedure, comparatively high yields and environmentally friendly features, provides a straightforward and inexpensive route to several chlorinated aromatic compounds.
Key words
chlorination - N-chlorosuccinimide - indoles - benzofurans - carbazoles - pyridines
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References
These authors contributed equally to this work.