Synthesis 2008(5): 690-692  
DOI: 10.1055/s-2008-1032165
SHORTPAPER
© Georg Thieme Verlag Stuttgart · New York

Direct Synthesis of Iodoarenes from Aromatic Substrates Using Molecular ­Iodine

Md. Delwar Hossain, Juzo Oyamada, Tsugio Kitamura*
Department of Chemistry and Applied Chemistry, Faculty of Science and Engineering, Saga University, Honjo-machi, Saga 840-8502, Japan­
Fax: +81(952)288548; e-Mail: kitamura@cc.saga-u.ac.jp;
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Publikationsverlauf

Received 3 October 2007
Publikationsdatum:
08. Februar 2008 (online)

Abstract

Easy laboratory procedures for oxidative iodination of aromatic substrates are presented. One procedure includes the iodination using molecular iodine, concentrated sulfuric acid, and potassium peroxodisulfate, and another uses a reagent system containing molecular iodine, potassium peroxodisulfate, and tri­fluoroacetic acid. These procedures are especially effective for benzene and less deactivated aromatic substrates, such as halobenzenes, trifluoromethylbenzene, and benzoic acid.