Indium-Mediated Allylation and Propargylation of Isatins: A Facile Synthesis of 3-Substituted 3-Hydroxyoxindoles

Abstract

Isatins undergo efficient allylation/propargylation when reacted with allyl/propargyl bromide in the presence of indium and sodium iodide to afford the corresponding 3-substituted 3-hydroxyoxindoles.

Key words

indium - allylations - propargylation - isatins - oxindoles

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