Synthesis 2003(15): 2368-2372  
DOI: 10.1055/s-2003-42395
PAPER
© Georg Thieme Verlag Stuttgart · New York

Synthesis and Utility of α-Methoxy Phosphonates with a 1,3,2-Dioxaphosphorinane Ring

Manab Chakravarty, B. Srinivas, C. Muthiah, K. C. Kumara Swamy*
School of Chemistry, University of Hyderabad, Hyderabad - 500046, AP, India
Fax: +91(40)23012460; e-Mail: kckssc@uohyd.ernet.in.;
Weitere Informationen

Publikationsverlauf

Received 10 July 2003
Publikationsdatum:
29. September 2003 (online)

Abstract

Synthesis of several α-methoxy phosphonates with the phosphorus as a part of 1,3,2-dioxaphosphorinane ring by the simple reaction of (OCH2CMe2CH2O)PCl with acetals is described. Analogous methoxy phosphonates using (±) (C20H12O2)PCl were also synthesized using the same route. Utility of these phosphonates in the synthesis of vinyl ethers via the Horner-Wadsworth-Emmons [HWE] reaction is demonstrated.