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Synthesis 2003(5): 0735-0741
DOI: 10.1055/s-2003-38080
PAPER
© Georg Thieme Verlag Stuttgart ˙ New York

A Convenient Synthesis of 2,3,4,5-Functionalised Thieno[2,3-b]thiophenes

Geoffroy Sommen, Alain Comel, Gilbert Kirsch*
Laboratoire d’Ingénierie Moléculaire et Biochimie Pharmacologique, Faculté des Sciences, Ile du Saulcy, 57045 Metz Cedex, France
e-Mail: kirsch@sciences.univ-metz.fr;
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Publication History

Received 5 December 2002
Publication Date:
21 March 2003 (online)

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Abstract

A two steps simple synthesis of 2,3,4,5-functionalised thieno[2,3-b]thiophenes 2-6 from ketene dimethylthioacetals is described.

Key words

bicyclic compounds - chemoselectivity - cyclisation - heterocycles - thiols

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Sommen, G.; Comel, A.; Kirsch, G. Tetrahedron, submitted.