Synthesis 2002(13): 1819-1822
DOI: 10.1055/s-2002-33911
PAPER
© Georg Thieme Verlag Stuttgart · New York

A New Chiral Route to Optically Pure (+)- and (-)-cis-endo-4-Oxatricyclo[5.2.1.02,6]dec-8-en-3-one

Katsufumi Suzuki, Kohei Inomata*
Tohoku Pharmaceutical University, 4-4-1 Komatsushima, Aoba-ku, Sendai 981-8558, Japan
Fax: +81(22)2752013; e-Mail: inomata@tohoku-pharm.ac.jp;
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Publikationsverlauf

Received 13 May 2002
Publikationsdatum:
09. September 2002 (online)

Abstracts

cis-endo-4-Oxatricyclo[5.2.1.02,6]dec-8-en-3-one has been prepared from known chiral hydroxydicyclopentadiene by sequential oxidative cleavage of cis-oriented glycols as the key steps.

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Preliminary results of this work were presented at The 121 st Annual Meeting of the Pharmaceutical Society of Japan Sapporo, Japan, March 28-30, 2001. See abstracts Vol. 2, 22.