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Synthesis 2000; 2000(10): 1372-1374
DOI: 10.1055/s-2000-7099
short paper
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Lipase-Mediated Preparation of Enantiopure Isolevoglucosenone

Kohei Kadota* , Adel S. ElAzab, Takahiko Taniguchi, Kunio Ogasawara
  • *Pharmaceutical Institute, Tohoku University, Aobayama, Sendai 980-8578, Japan; Fax + 81(22)2 17 68 45; E-mail: konol@mail.cc.tohoku.ac.jp
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Publication Date:
31 December 2000 (online)

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A route to enantiopure isolevoglucosenone, a regioisomer of levoglucosenone and a potential chiral building block, has been developed by employing lipase-mediated kinetic resolution as the key step.

isolevoglucosenone - lipase-mediated kinetic resolution - enantioselective kinetic resolution - enantioselective hydrolysis - chiral building block