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Synthesis 1994; 1994(8): 805-808
DOI: 10.1055/s-1994-25579
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Ester-Imine Condensation Mediated by Potassium tert-Butoxide: Synthesis of ß-Lactams and 3,4-Dihydropyridin-2-ones

Gianfranco Cainelli* , Mauro Panunzio, Daria Giacomini, Bruno Di Simone, Roberto Camerini
  • *Dipartimento di Chimica "G. Ciamician", Università di Bologna and C.S.F.M.-C.N.R., Via Selmi 2, I-40126, Bologna, Italy
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Publication Date:
17 September 2002 (online)

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The utility of the weak base potassium tert-butoxide has been successfully demonstrated in the synthesis of ß-lactams and 3, 4-dihydropyridin-2-ones starting from esters and imines.

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