Download PDF
Synthesis 1992; 1992(12): 1276-1279
DOI: 10.1055/s-1992-26357
paper
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.

A Facile Synthesis of 2-Phosphoryl-Substituted 3-Hydroxyindole Derivatives

Axel Couture* , Eric Deniau, Pierre Grandclaudon
  • *Laboratoire de Chimie Organique Physique, URA CNRS No 351, Université des Sciences et Technologies de Lille, F-59655 Villeneuve d'Ascq Cédex, France
Further Information

Publication History

Publication Date:
29 April 2002 (online)

  PDF Download  Permissions and Reprints All articles of this category

A variety of 1-substituted 2-diphenylphosphinoyl-3-hydroxy-1H-indoles 5a-d and 2-dimethoxyphosphoryl-3-hydroxy-1H-indoles 6a,c have been efficiently prepared by base-induced intramolecular cyclization of the appropriate Horner-Wittig and Wadsworth-Emmons reagents, 2-[(diphenylphosphinoyl)methylamino]-N,N-diethylbenzamides 3a-d and 2-[(dimethoxyphosphoryl)methylamino]-N,N-diethylbenzamides 4a,c, respectively.

      >