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Synthesis 1989; 1989(12): 951-953
DOI: 10.1055/s-1989-27442
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Synthesis of N-Boc-Statine and epi-Statine

Peter G. M. Wuts* , Sterling R. Putt
  • *Chemical Process and Development, 1500-230-4, The Upjohn Co, Kalamazoo, MI 49001, USA
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Publikationsdatum:
02. Mai 2002 (online)

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The amino acid statine and its C-3 epimer have been prepared stereoselectively as their N-tert-butoxycarbonyl (N-Boc) derivatives 8 and 9 from (S)-Boc-leucinal (1), and (S)-(2) and (R)-1,1,2-triphenyl-2-acetoxythanol (3), respectively.

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