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Synthesis 1987; 1987(5): 511-512
DOI: 10.1055/s-1987-27988
DOI: 10.1055/s-1987-27988
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data processing and storage.A New and Efficient One-Pot Preparation of Alkyl Halides From Alcohols
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Publication History
Publication Date:
18 September 2002 (online)
Primary alkanols and 2-alkenols are converted into the corresponding halides in high yield by a one-pot, two-step reaction via transformation into intermediate trifluoroacetates followed by nucleophilic substitution with lithium halides.