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Synthesis 1987; 1987(5): 491-493
DOI: 10.1055/s-1987-27979
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Synthesis of (R) and (S)-α-Hydroxy-β-Amino Propionaldehydes and Propionic Acids From D-Mannitol

A. Dureault* , I. Tranchepain, J. C. Depezay
  • *Laboratoire de Chimie et Biochimie Pharmacologiques et Toxicologiques (UA 400 CNRS), Université René Descartes, 45 rue des Saints-Pères, F-75270 Paris Cedex 06, France
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Publication Date:
18 September 2002 (online)

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An easy method to prepare (R)- and (S)-isoserine from D-mannitol is reported. Suitably protected (R)- or (S)-α-hydroxy-β-aminopropanals are also accessible by the same route.

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