Download PDF
Synthesis 1986; 1986(2): 117-120
DOI: 10.1055/s-1986-31490
paper
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.

New Convergent Synthesis of Germacranolides with a trans-Fused γ-Lactone

Gordon L. Lange* , Moses Lee
  • *Guelph-Waterloo Centre for Graduate Work in Chemistry, Department of Chemistry and Biochemistry, University of Guelph, Guelph, Ontario, N1G 2W1, Canada
Further Information

Publication History

Publication Date:
20 August 2002 (online)

  PDF Download  Permissions and Reprints All articles of this category

A new concerted approach to the formation of the trans-fused γ-lactone which bridges C-6 and C-7 in the germacranolide family of sesquiterpenoids is reported. Starting with enone 3 and using this approach, the synthesis of 2, a geometric isomer of the naturally occurring germacranolide 1, is outlined.

      >