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Synthesis 2009(13): 2171-2174  
DOI: 10.1055/s-0029-1216858
PAPER
© Georg Thieme Verlag Stuttgart ˙ New York

Pyrrolo[3,2,1-ij]quinolin-4-one and Pyrrolo[3,2,1-ij]quinolin-6-one

Hamish McNab*, David J. Nelson, Emma J. Rozgowska
School of Chemistry, The University of Edinburgh, West Mains Road, Edinburgh, EH9 3JJ, UK
Fax: +44(131)6504743; e-Mail: H.McNab@ed.ac.uk;
Further Information

Publication History

Received 2 February 2009
Publication Date:
02 June 2009 (online)

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Abstract

The parent pyrrolo[3,2,1-ij]quinolin-4-one and pyrrolo[3,2,1-ij]quinolin-6-one ring systems were made by pyrolysis of appropriate acrylates. In the first case, the cyclisation was effected by flash vacuum pyrolysis (FVP) at 950 ˚C, in the second case a cyclisation-dehydrogenation was carried out in one step by FVP over a tungsten trioxide catalyst at 525 ˚C.

Key words

gas-phase reactions - cyclisations - heterocycles - pyrolysis - ketenes

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McNab, H.; O’Neill, W. J.; Rozgowska, E. J. unpublished work.