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Synthesis 2009(8): 1348-1354  
DOI: 10.1055/s-0028-1088032
PAPER
© Georg Thieme Verlag Stuttgart ˙ New York

Efficient Synthesis of Two Sialylated Tetrasaccharides Found in Goat Milk

Pintu Kumar Mandal, Anup Kumar Misra*
Division of Molecular Medicine, Bose Institute, A. J. C. Bose Centenary Campus, P-1/12, C.I.T. Scheme VII-M, Kolkata 700054, India
Fax: +91(33)23553886; e-Mail: akmisra69@rediffmail.com;
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Publikationsverlauf

Received 24 November 2008
Publikationsdatum:
25. März 2009 (online)

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Abstract

Two regioisomeric sialylated tetrasaccharides found in goat milk have been obtained in excellent yield by a concise synthesis using a common disaccharide intermediate. Regioselective glycosylations and a minimal number of protecting-group manipulations are the key features of this synthetic strategy.

Key words

oligosaccharides - glycosylations - sialic acid - goat milk - tetrasaccharides

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