Thromb Haemost 2008; 99(06): 1121
DOI: 10.1160/TH08-04-0205
Letters to the Editor
Schattauer GmbH

The JAK2 V617F mutation in patients with cerebral venous thrombosis: A rebuttal

Valerio De Stefano
1   Institute of Hematology, Catholic University, Rome, Italy
,
Elena Rossi
1   Institute of Hematology, Catholic University, Rome, Italy
,
Tommaso Za
1   Institute of Hematology, Catholic University, Rome, Italy
,
Patrizia Chiusolo
1   Institute of Hematology, Catholic University, Rome, Italy
,
Giuseppe Leone
1   Institute of Hematology, Catholic University, Rome, Italy
› Author Affiliations
Further Information

Publication History

Received 02 April 2008

Accepted 10 April 2008

Publication Date:
28 November 2017 (online)

 

 
  • References

  • 1 Tefferi A, Thiele J, Orazi A. et al. Proposals and rationale for revision of the World Health Organization diagnostic criteria for polycythemia vera, essential thrombocythemia, and primary myelofibrosis: recommendations from an ad hoc international expert panel. Blood 2007; 110: 1092-1097.
  • 2 Kiladjian J-J, Cervantes F, Leebeek FWG. et al. The impact of JAK2 and MPL mutations on diagnosis and prognosis of splanchnic vein thrombosis. A report on 241 cases. Blood. 2008 epub ahead of print.
  • 3 Stam J. Thrombosis of the cerebral veins and sinuses. N Engl J Med 2005; 352: 1791-1798.
  • 4 Bazzan M, Tamponi G, Schinco P. et al. Thrombosis-free survival and life expetancy in 187 consecutive patients with essential thrombocythemia. Ann Hematol 1999; 78: 539-543.
  • 5 Baxter EJ, Scott LM, Campbell PJ. et al. Acquired mutation of the tyrosine kinase JAK2 in human myeloproliferative disorders. Lancet 2005; 365: 1054-1061.
  • 6 De Stefano V, Fiorini A, Rossi E. et al. Incidence of the JAK2 V617F mutation among patients with splanchnic or cerebral venous thrombosis and without overt chronic myeloproliferative disorders. J Thromb Haemost 2007; 5: 708-714.
  • 7 Bellucci S, Cassinat B, Bonnin N. et al. The V617F JAK2 mutation is not a frequent event in patients with cerebral venous thrombosis without overt chronic myeloproliferative disorder. Thromb Haemost 2008; 99: 1119-1120.