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Horm Metab Res 1981; 13(11): 648-649
DOI: 10.1055/s-2007-1019362
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© Georg Thieme Verlag, Stuttgart · New York

Effect of Clonidine on Growth Hormone and Glucagon Secretion

S. Lal1 , G. Tolis1 , T. J. McDonald2 , P. Cervantes1 , J. Dupré2
  • 1McGill University, Canada
  • 2University of Western Ontario, Canada
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Publication History

1981

1981

Publication Date:
14 March 2008 (online)

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Summary

The effect of clonidine (0.15 mg i.v.) on circulating GH, glucagons and glucose concentrations was measured in six normal subjects. GH and glucose increased but glucagon secretion remained unchanged. These data indicate that in man clonidine-induced GH secretion is not mediated by a stimulatory effect of clonidine on glucagon secretion and that alpha-adrenergic mechanisms have little role in the regulation of basal glucagons secretion.

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