Intravenous Glucose Tolerance Tests in the New Zealand Strains of Mice

Summary

Intravenous glucose tolerance tests (I.V.G.T.T.) were carried out in fasting NZO, NZB and NZB/W mice. NZO and NZB mice exhibited an impaired rate of glucose decay, while NZB/W mice cleared glucose very rapidly. The possibility that autoimmune processes are responsible for the glucose intolerance observed in NZO and NZB mice is discussed.

Key-Words:

New Zealand Mice - Obesity - I.V.G.T.T.