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Horm Metab Res 1986; 18(3): 182-184
DOI: 10.1055/s-2007-1012265
Clinical

© Georg Thieme Verlag, Stuttgart · New York

Twenty-Four Hour Blood Glucose Profiles during Insulin and Insulin Plus Aprotinin Subcutaneous Administration in Type I Diabetes

M. Lunetta, E. Napoli, L. Sudano, R. Leonardi, L. Mughini
  • Department of 2nd Medical Pathology and Metabolic Diseases, University of Catania, Catania, Italy
Further Information

Publication History

1983

1984

Publication Date:
14 March 2008 (online)

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Summary

Twenty-four hour glucose levels were measured in nineteen insulin treated type I diabetics both during insulin plus aprotinin treatments and insulin by itself. Aprotinin - a proteinase inhibitor agent - administered together with insulin (10.000 KIU for every 10 U.I. insulin) did not influence the effect of insulin on blood glucose levels.

These findings do not support the hypothesis that the administration of aprotinin together with insulin can be clinically useful in conventional insulin treated diabetic patients.

Key-Words

Diabetes - Insulin Resistance - Aprotinin - Blood Glucose

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