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Planta Med 1993; 59(3): 232-239
DOI: 10.1055/s-2006-959658
Paper

© Georg Thieme Verlag Stuttgart · New York

Ontogenic Aspects of Ginkgolide Production in Ginkgo biloba

Hoon Huh1 , 2 , E. John Staba1 , 3
  • 1Department of Medicinal Chemistry, College of Pharmacy, University of Minnesota, Minneapolis, Minnesota 55455, U.S.A.
  • 2Present address: Pharmaceutical Biology, University of Munich, Karlstraße 29, D(W)-8000 Munich 2, Federal Republic of Germany
  • 3Address for correspondence
Further Information

Publication History

1992

1992

Publication Date:
04 January 2007 (online)

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Abstract

The ontogenic aspects of ginkgolide production were studied by using Ginkgo biloba seedlings, greenhouse plants, young trees, mature trees cuttings, and plant tissue cultures. Ginkgolide yield appeared to be increased with the age of the plants when the plants were grown under the same environmental conditions. Ginkgolide content in the leaves was increased when seedlings, young plants, and young trees were treated with fluridone, a carotenoid biosynthesis inhibitor. Ginkgolides appeared to be independently biosynthesized in leaves and roots of the Ginkgo and stored in root bark and stem as more hydroxylated forms such as ginkgolide B or ginkgolide C.

Key words

Ginkgo biloba - ginkgolides - ginkgolide production - ontogenesis aspects.

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