Four New Taxoids from Taxus cuspidata var. nana

Hiroshi Morita; Akira Gonda; Lan Wei; Yukinori Yamamura; Hideki Wakabayashi; Koichi Takeya; Hideji Itokawa

doi:10.1055/s-2006-957402

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Planta Med 1998; 64(2): 183-186
DOI: 10.1055/s-2006-957402

Letters

Letter
© Georg Thieme Verlag Stuttgart · New York

Four New Taxoids from Taxus cuspidata var. nana

Hiroshi Morita, Akira Gonda, Lan Wei, Yukinori Yamamura, Hideki Wakabayashi, Koichi Takeya, Hideji Itokawa

Department of Pharmacognosy, School of Pharmacy, Tokyo University of Pharmacy and Life Science, Hachioji, Tokyo, Japan

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Publication History

1997

1997

Publication Date:
04 January 2007 (online)

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Abstract

Four new taxoids (1-4), showing cytotoxic activity, have been isolated from the stems of Taxus cuspidata Sieb. et. Zucc. var. nana Rehder. Their structures were elucidated by extensive 2D NMR methods including ¹H-¹H COSY, TOCSY, HMBC, HMQC, and phase sensitive ROESY spectra.

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