Planta Med 2005; 71(2): 160-164
DOI: 10.1055/s-2005-837784
Original Paper
Natural Product Chemistry
© Georg Thieme Verlag KG Stuttgart · New York

New Aromatic Compounds from the Marine Mangrove Bruguiera gymnorrhiza

Li Han1 , 2 , Xueshi Huang1 , Isabel Sattler1 , Ute Moellmann1 , Hongzheng Fu2 , Wenhan Lin2 , Susanne Grabley1
  • 1Hans-Knöll Institute for Natural Products Research, Jena, Germany
  • 2National Research Laboratory of Natural and Biomimetic Drugs, Peking University, Beijing, P. R. China
Further Information

Publication History

Received: April 20, 2004

Accepted: August 29, 2004

Publication Date:
24 February 2005 (online)

Abstract

The phytochemical investigation of the stem of Bruguiera gymnorrhiza yielded five new aromatic compounds (1 - 5), of which the bruguierols A - C (1 - 3) represent a new structural skeleton in natural product chemistry. All structures have been determined by NMR spectroscopic studies. Among them, 3 showed moderate activity against Gram-positive and Gram-negative bacteria including mycobacteria and resistant strains (MICs 12.5 μg/mL).

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Dr. Isabel Sattler

Hans-Knöll-Institute for Natural Products Research

Beutenbergstr. 11a

07745 Jena

Germany

Phone: +49-3641-656920.

Fax: +49-3641-656679.

Email: isabel.sattler@hki-jena.de