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Synlett 1992; 1992(4): 295-296
DOI: 10.1055/s-1992-21344
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Facile Synthesis of 1,4-Benzodiazepin-5-ones via Intramolecular Aza-Wittig Reaction1

Shoji Eguchi* , Keizo Yamashita, Yuji Matsushita
  • *Institute of Applied Organic Chemistry, Faculty of Engineering, Nagoya University, Furo-cho, Chikusa-ku, Nagoya 464-01, Japan
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Publication Date:
08 March 2002 (online)

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A new and efficient synthetic method for 4-alkoxy-1,4-benzodiazepin-5-ones 4 has been developed by utilizing tandem Staudinger reaction and intramolecular aza-Wittig reaction of [N-(o-azidobenzoyl)]-α-amino esters 3.

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