Psychother Psychosom Med Psychol 2018; 68(12): 516-524
DOI: 10.1055/s-0043-124473
Originalarbeit
© Georg Thieme Verlag KG Stuttgart · New York

Prävalenz und Phänomenologie fraglich psychotischer Symptome bei Borderline Persönlichkeitsstörungen

Assoziationen mit Suizidversuchen und Inanspruchnahme stationär-psychiatrischer BehandlungPrevalence and Phenomenology of Psychotic-Like Symptoms in Borderline Personality DisordersAssociations with Suicide Attempts and Use of Psychiatric Inpatient Treatment
Katrin Schroeder
1   Psychiatrie und Psychotherapie, Universitätsklinikum Hamburg-Eppendorf
,
Anja Schätzle
1   Psychiatrie und Psychotherapie, Universitätsklinikum Hamburg-Eppendorf
,
Pauline Kowohl
1   Psychiatrie und Psychotherapie, Universitätsklinikum Hamburg-Eppendorf
,
Lisa Leske
1   Psychiatrie und Psychotherapie, Universitätsklinikum Hamburg-Eppendorf
,
Christian G. Huber
2   Universitäre Psychiatrische Kliniken Basel, Universität Basel, Schweiz
,
Ingo Schäfer
1   Psychiatrie und Psychotherapie, Universitätsklinikum Hamburg-Eppendorf
› Author Affiliations
Further Information

Publication History

eingereicht 27 January 2017

akzeptiert 22 November 2017

Publication Date:
19 January 2018 (online)

Zusammenfassung

Hintergrund Eine Subgruppe von Patientinnen mit Borderline Persönlichkeitsstörung (BPS) berichtet von fraglich psychotischen Symptomen. Die Angaben zur Häufigkeit variieren beträchtlich (bis zu 50% Betroffene). Untersuchungen in Deutschland stehen bislang aus. Weiterhin sind die genaue Phänomenologie dieser Symptome und die Auswirkungen auf Suizidalität und Inanspruchnahme stationärer psychiatrischer Behandlung bisher unklar.

Ziel der Arbeit Es erfolgte die Untersuchung der Prävalenzen und Phänomenologie der fraglich psychotischen Symptome. Assoziationen zwischen letzteren und Suizidalität sowie Inanspruchnahme stationärer psychiatrischer Behandlung wurden unter Berücksichtigung weiterer Einflussfaktoren überprüft.

Methodik Fraglich psychotische Symptome wurden bei 95 BPS-Patientinnen mit dem Strukturierten Klinischen Interview-I erhoben. Zur Überprüfung der Assoziationen zwischen diesen Symptomen und Suizidalität sowie Inanspruchnahme stationärer psychiatrischer Behandlung wurden Korrelations- und Regressionsanalysen berechnet. PTBS-Symptomatik, Ausprägung der BPS und Depressivität wurden berücksichtigt.

Ergebnisse 36% der Pat. berichteten von vielgestaltigen und langanhaltenden Wahrnehmungsveränderungen (WV) und 21% von ebensolchen Wahnvorstellungen. Die Anzahl der Suizidversuche war mit Wahnerleben, WV und Schwere der PTBS-Symptomatik, Ausprägung der BPS und Depressivität assoziiert. 25,8% der Varianz zur Vorhersage der Anzahl der Suizidversuche wurde durch Wahnerleben und PTBS-Symptomschwere erklärt. Für das Alter bei Ersthospitalisation zeigten sich weniger und für die Anzahl der Hospitalisationen keine Assoziationen.

Diskussion Fraglich psychotische Symptome sollten nicht trivialisiert werden, was möglicherweise durch die Nutzung von Begrifflichkeiten wie Pseudohalluzinationen oder vorübergehende paranoide Vorstellungen geschieht und können insbesondere mit Suizidalität assoziiert sein, wodurch das klinische Bild erschwert wird.

Abstract

Background Psychotic-like symptoms are found in a subgroup of borderline patients (BPD). Reported prevalence is heterogeneous (up to 50% affected). Investigations in Germany have not been conducted so far. Furthermore, the precise phenomenology of the psychotic symptoms and the effects on suicidal behavior and the use of inpatient psychiatric treatment are unclear.

Objectives The aim of the study was to investigate prevalence rates and phenomenology of psychotic-like symptoms. Associations between the latter and suicidality as well as the use of inpatient psychiatric treatment were examined. Further influencing factors were taking into account.

Methods Psychotic-like symptoms were assessed with the Structured Clinical Interview-I in 95 BPD patients. To investigate the associations between psychotic-like symptoms and suicidality as well as the use of inpatient psychiatric treatment, correlation and regression analyzes were calculated, considering severity of PTSD, BPD and depression.

Results 36% of the patients reported alterations of perception and 21% delusions, both multiform and long lasting. The number of suicide attempts was associated with delusions, alterations of perception and severity of PTSD, BPS, and depression. Only delusions and severity of PTSD explained together 25.8% of the variance for the prediction of the number of suicide attempts. Age of initial hospitalization showed fewer and number of hospitalizations no associations at all.

Discussion Psychotic-like symptoms should not be trivialized, which may happen by using terms such as pseudo-hallucinations or transient paranoid ideas, and may be particularly associated with suicidal tendencies complicating the clinical course.

 
  • Literatur

  • 1 Stern A. Psychoanalytic investigation of and therapy in the border line group of neuroses psychoanal Q. 1938; 7: 467-489
  • 2 Pope Jr HG, Jonas JM, Hudson JI. et al. The validity of DSM-III borderline personality disorder. A phenomenologic, family history, treatment response, and long-term follow-up study. Arch Gen Psychiatry 1983; 40: 23-30
  • 3 World Health Organization W. The ICD-10 classification of mental and behavioural disorders: primary health care classification. Geneva (Siwtzerland): WHO; 1993
  • 4 Glaser JP, Van Os J, Thewissen V. et al. Psychotic reactivity in borderline personality disorder. Acta Psychiatr Scand 2010; 121: 125-134
  • 5 Pope Jr. HG, Jonas JM, Hudson JI. et al. An empirical study of psychosis in borderline personality disorder. Am J Psychiatry 1985; 142: 1285-1290
  • 6 Zanarini MC, Gunderson JG, Frankenburg FR. Cognitive features of borderline personality disorder. Am J Psychiatry 1990; 147: 57-63
  • 7 Coid J, Yang M, Bebbington P. et al. Borderline personality disorder: health service use and social functioning among a national household population. Psychol Med 2009; 39: 1721-1731
  • 8 van der Zwaard R, Polak MA. Pseudohallucinations: a pseudoconcept? A review of the validity of the concept, related to associate symptomatology. Compr Psychiatry 2001; 42: 42-50
  • 9 Schroeder K, Fisher HL, Schafer I. Psychotic symptoms in patients with borderline personality disorder: prevalence and clinical management. Curr Opin Psychiatry 2013; 26: 113-119
  • 10 Moskowitz A, Corstens D. Auditory hallucinations: Psychotic symptom or dissociative experience?. Journal of Psychological Trauma 2008; 6: 35-63
  • 11 Laroi F, Sommer IE, Blom JD. et al. The Characteristic features of auditory verbal hallucinations in clinical and nonclinical groups: State-of-the-art overview and future directions. Schizophr Bull 2012; 38: 724-733
  • 12 Chopra HD, Beatson JA. Psychotic symptoms in borderline personality disorder. Am J Psychiatry 1986; 143: 1605-1607
  • 13 Slotema CW, Daalman K, Blom JD. et al. Auditory verbal hallucinations in patients with borderline personality disorder are similar to those in schizophrenia. Psychol Med 2012; 42: 1873-1878
  • 14 Zonnenberg C, Niemantsverdriet MB, Blom JD. et al. [Auditory verbal hallucinations in patients with borderline personality disorder]. Tijdschrift voor psychiatrie 2016; 58: 122-129
  • 15 Kingdon DG, Ashcroft K, Bhandari B. et al. Schizophrenia and borderline personality disorder: similarities and differences in the experience of auditory hallucinations, paranoia, and childhood trauma. J Nerv Ment Dis 2010; 198: 399-403
  • 16 Tschoeke S, Steinert T, Flammer E. et al. Similarities and differences in borderline personality disorder and schizophrenia with voice hearing. J Nerv Ment Dis 2014; 202: 544-549
  • 17 Haddock G, McCarron J, Tarrier N. et al. Scales to measure dimensions of hallucinations and delusions: the psychotic symptom rating scales (PSYRATS). Psychological Medicine 1999; 29: 879-889
  • 18 APA. Diagnostic and statistical manual of mental disorders: DSM-5. Washington, DC: American Psychiatric Association; 2015
  • 19 APA. Diagnostic & statistical manual of mental disorders. Fourth Edition Text Revision (DSM-IV-TR) Washington, DC: American Psychiatric Publishing; 2000
  • 20 Miller FT, Abrams T, Dulit R. et al. Psychotic symptoms in patients with borderline personality disorder and concurrent axis I disorder. Hosp Community Psychiatry 1993; 44: 59-61
  • 21 Suzuki H, Tsukamoto C, Nakano Y. et al. Delusions and hallucinations in patients with borderline personality disorder. Psychiatry Clin Neurosci 1998; 52: 605-610
  • 22 Yee L, Korner AJ, McSwiggan S. et al. Persistent hallucinosis in borderline personality disorder. Compr Psychiatry 2005; 46: 147-154
  • 23 Adams B, Sanders T. Experiences of psychosis in borderline personality disorder: a qualitative analysis. J Ment Health 2011; 20: 381-391
  • 24 Pearse LJ, Dibben C, Ziauddeen H. et al. A study of psychotic symptoms in borderline personality disorder. J Nerv Ment Dis 2014; 202: 368-371
  • 25 Grant BF, Chou SP, Goldstein RB. et al. Prevalence, correlates, disability, and comorbidity of DSM-IV borderline personality disorder: results from the Wave 2 National Epidemiologic Survey on Alcohol and Related Conditions. J Clin Psychiatry 2008; 69: 533-545
  • 26 Zanarini MC, Frankenburg FR, Reich DB. et al. Fluidity of the subsyndromal phenomenology of borderline personality disorder over 16 Years of prospective follow-up. Am J Psychiatry 2016; 173: 688-694
  • 27 Zanarini MC, Frankenburg FR, Reich DB. et al. Attainment and stability of sustained symptomatic remission and recovery among patients with borderline personality disorder and axis II comparison subjects: a 16-year prospective follow-up study. Am J Psychiatry 2012; 169: 476-483
  • 28 Bohus M. Zur Versorgungssituation von Borderline-Patienten in Deutschland. Persönlichkeitsstör Theorie Ther 2007; 11: 149-153
  • 29 Soloff PH, Lynch KG, Kelly TM. Childhood abuse as a risk factor for suicidal behavior in borderline personality disorder. J Pers Disord 2002; 16: 201-214
  • 30 Black DW, Blum N, Pfohl B. et al. Suicidal behavior in borderline personality disorder: prevalence, risk factors, prediction, and prevention. J Pers Disord 2004; 18: 226-239
  • 31 Zanarini MC, Frankenburg FR, Hennen J. et al. The McLean Study of Adult Development (MSAD): overview and implications of the first six years of prospective follow-up. J Pers Disord 2005; 19: 505-523
  • 32 Paris J, Zweig-Frank H. A 27-year follow-up of patients with borderline personality disorder. Compr Psychiatry 2001; 42: 482-487
  • 33 Slotema CW, Niemantsverdriet MB, Blom JD. et al. Suicidality and hospitalisation in patients with borderline personality disorder who experience auditory verbal hallucinations. European psychiatry: the journal of the Association of European Psychiatrists 2017; 41: 47-52
  • 34 Kjelby E, Sinkeviciute I, Gjestad R. et al. Suicidality in schizophrenia spectrum disorders: the relationship to hallucinations and persecutory delusions. European psychiatry: the journal of the Association of European Psychiatrists 2015; 30: 830-836
  • 35 Fujita J, Takahashi Y, Nishida A. et al. Auditory verbal hallucinations increase the risk for suicide attempts in adolescents with suicidal ideation. Schizophr Res 2015; 168: 209-212
  • 36 Fydrich T, Renneberg B, Schmitz B et al. SKID II. Strukturiertes Klinisches Interview für DSM-IV, Achse II: Persönlichkeitsstörungen. Interviewheft. Eine deutschsprachige, erw. Bearb. d. amerikanischen Originalversion d. SKID-II von: MB First, RL Spitzer, M. Gibbon, JBW Williams, L. Benjamin, (Version 3/96); 1997
  • 37 Wittchen HU, Zaudig M, Fydrich T. Strukturiertes Klinisches Interview für DSM-IV: Handanweisung. Göttingen: Hogrefe-Verlag; 1997
  • 38 Beck AT, Steer RA, Brown GK. Beck Depression Inventory. 2nd edn. Manual San Antonio: The Psychological Corporation; 1996
  • 39 Hautzinger M, Keller F, Kühner C. et al. Deutsche Bearbeitung und Handbuch zum BDI II. Frankfurt a. M.: Harcourt Test Services; 2006
  • 40 Kuhner C, Burger C, Keller F. et al. [Reliability and validity of the Revised Beck Depression Inventory (BDI-II). Results from German samples]. Nervenarzt 2007; 78: 651-656
  • 41 Foa EB. Posttraumatic Stress Diagnostic Scale Manual. In National Computer Systems Inc.; 1995
  • 42 Ehlers A, Steil R, Winter H. et al. Deutsche Übersetzung der Posttraumatic Stress Diagnostic Scale (PDS). Oxford: University Warneford Hospital; 1996
  • 43 Griesel D, Wessa M, Flor H. Psychometric Qualities of the German Version of the Posstraumatic Diagnostic Scale (PTDS). In: Psychological Assessment 2006; 262-268
  • 44 Cohen J. Statistical power analysis for the behavioral sciences. 2. Aufl New Jersey: Lawrence Erlbaum; 1988
  • 45 Schneider K. Psychischer Befund und Psychiatrische Diagnose. Leipzig, Germany: Georg Thieme Verlag; 1939
  • 46 Vogel M, Meier J, Gronke S. et al. Differential effects of childhood abuse and neglect: mediation by posttraumatic distress in neurotic disorder and negative symptoms in schizophrenia?. Psychiatry Res 2011; 189: 121-127
  • 47 Linehan MM. Cognitive-behavorial treatment of borderline personality disorder. New York: Guildford Press; 1993
  • 48 Bateman AW, Fonagy P. Mentalization based treatment for borderline personality disorder: A Practical Guide. Oxford, UK: Oxford University Press; 2006
  • 49 Young JE, Klosko J, Weishaar ME. Schema therapy: A practioner’s guide. New York: Guilford; 2003
  • 50 Kernberg OF, Yeomans FE, Clarkin JF. et al. Transference focused psychotherapy: overview and update. Int J Psychoanal 2008; 89: 601-620
  • 51 Bohus M, Kroger C. [Psychopathology and psychotherapy of borderline personality disorder: State of the art.]. Nervenarzt 2011; 82: 16-24
  • 52 Gaudiano BA. Is symptomatic improvement in clinical trials of cognitive-behavioral therapy for psychosis clinically significant?. J Psychiatr Pract 2006; 12: 11-23
  • 53 Zimmermann G, Favrod J, Trieu VH. et al. The effect of cognitive behavioral treatment on the positive symptoms of schizophrenia spectrum disorders: a meta-analysis. Schizophr Res 2005; 77: 1-9
  • 54 Gould RA, Mueser KT, Bolton E. et al. Cognitive therapy for psychosis in schizophrenia: an effect size analysis. Schizophr Res 2001; 48: 335-342
  • 55 Slotema CW, Blom JD, Deen M. et al. Negative beliefs about voices in patients with borderline personality disorder are associated with distress: a plea for cognitive-behavioural therapy. Psychopathology 2017; DOI: 10.1159/000477669.
  • 56 Lieb K, Vollm B, Rucker G. et al. Pharmacotherapy for borderline personality disorder: Cochrane systematic review of randomised trials. Br J Psychiatry 2010; 196: 4-12
  • 57 Stoffers JM, Lieb K. Pharmacotherapy for borderline personality disorder–current evidence and recent trends. Curr Psychiatry Rep 2015; 17: 534
  • 58 Stoffers J, Vollm BA, Rucker G. et al. Pharmacological interventions for borderline personality disorder. The Cochrane database of systematic reviews 2010; DOI: 10.1002/14651858.CD005653.pub2: CD005653.