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Thromb Haemost 1962; 07(01): 095-105
DOI: 10.1055/s-0038-1655458
Originalarbeiten — Original Articles — Travaux Originaux
Schattauer GmbH

The Potency of Tissue Thromboplastic Suspensions[*]

Seymour Gollub
1   Samuel P. Mandell Laboratory of Research Surgery, Albert Einstein Medical Center, Southern Division, Philadelphia, Pennsylvania, and Sidney Hillman Medical Center, Philadelphia
,
Abramo C. Ottolenghi
1   Samuel P. Mandell Laboratory of Research Surgery, Albert Einstein Medical Center, Southern Division, Philadelphia, Pennsylvania, and Sidney Hillman Medical Center, Philadelphia
,
Lenore Lisbinsky
1   Samuel P. Mandell Laboratory of Research Surgery, Albert Einstein Medical Center, Southern Division, Philadelphia, Pennsylvania, and Sidney Hillman Medical Center, Philadelphia
,
Alex W. Uin
1   Samuel P. Mandell Laboratory of Research Surgery, Albert Einstein Medical Center, Southern Division, Philadelphia, Pennsylvania, and Sidney Hillman Medical Center, Philadelphia
1   Samuel P. Mandell Laboratory of Research Surgery, Albert Einstein Medical Center, Southern Division, Philadelphia, Pennsylvania, and Sidney Hillman Medical Center, Philadelphia
› Author Affiliations
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Publication History

Publication Date:
21 June 2018 (online)

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Summary

The potency of various human brain thromboplastic suspensions was estimated by two independent test systems. It was found that potency estimation using the in vitro system (clot acceleration) did not correlate with potency estimation of an in vivo system (thrombotic-lethal). However, good correlation between lethality and thromboplastinase labile phospholipid compartment was established. These findings are briefly discussed.

* Supported in part by grants # C 4546 and # E 3701 from The National Institutes of Health.


 

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